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Image Search Results
Journal: Cancers
Article Title: Targeted Nano-Drug Delivery of Colchicine against Colon Cancer Cells by Means of Mesoporous Silica Nanoparticles
doi: 10.3390/cancers12010144
Figure Lengend Snippet: In vitro cytotoxicity (as percent inhibition) of MSNs and MSNs functionalized with phosphonate functional groups (MSNsP) for biocompatibility evaluations in cancer and normal cell lines after 24, 48, and 72 h of incubation with cancer cells (liver, HepG2; prostate, PC3; and colon, HCT116) and normal fibroblasts (BJ1). ( A ) Cytotoxicity of MSNs towards cell lines. ( B ) Cytotoxicity of MSNsP towards cell lines. Note: A blue asterisk (*) indicates significant ( p < 0.05) differences between tested concentrations, whereas an orange asterisk (*) indicates significant differences between cell lines. NS, not significant. All data are expressed as mean ± SD.
Article Snippet: Human prostate adenocarcinoma PC3 cells (ATCC ® CRL-1435 TM ), human colon colorectal carcinoma HCT116 cells (ATCC ® CCL-247 TM ), human hepatic carcinoma HepG2 cells (ATCC ® HB-8065 TM ), and
Techniques: In Vitro, Inhibition, Functional Assay, Incubation
Journal: Cancers
Article Title: Targeted Nano-Drug Delivery of Colchicine against Colon Cancer Cells by Means of Mesoporous Silica Nanoparticles
doi: 10.3390/cancers12010144
Figure Lengend Snippet: In vitro cytotoxicity (as percent inhibition) of the proposed delivery system in cancer and normal cells after 24, 48, and 72 h of incubation with cells. ( A ) Anticancer effects on HepG2 cancer cells. ( B ) Anticancer effects on PC3 cancer cells. ( C ) Anticancer effects on HCT116 cancer cells. ( D ) Anticancer effects on BJ1 normal cells. Note: A blue asterisk (*) indicates significant ( p < 0.05) differences between tested concentrations, whereas an orange asterisk (*) indicates significant differences between tested samples (nanoformulations and COL). NS, not significant. All data are expressed as mean ± SD.
Article Snippet: Human prostate adenocarcinoma PC3 cells (ATCC ® CRL-1435 TM ), human colon colorectal carcinoma HCT116 cells (ATCC ® CCL-247 TM ), human hepatic carcinoma HepG2 cells (ATCC ® HB-8065 TM ), and
Techniques: In Vitro, Inhibition, Incubation